Showing posts with label control group. Show all posts
Showing posts with label control group. Show all posts

New studies suggest that lingonberries could prevent weight gain and obesity-related diseases; in a study based on mice, researchers found that these berries helped to prevent obesity. The mice were genetically modified to become obese and develop features of obesity, and in the experiment the mice were fed a high fat diet for 13 weeks as a way of mimicking the fatty western diet. However, there were eight different groups of mice given eight different types of freeze-dried berry alongside the diet of fatty foods to see if the mice were affected in terms of weight gain. Two further control groups were given no berries, one of which ate the same high fat diet and another a low-fat diet. The final result was that all of the mice gained weight but the mice who were given the berries gained less weight. Lingonberries are a wild fruit popular in Scandinavia and, in studies, were the best at showing the lowest increase in body fat, cholesterol and blood sugar of all the high fat groups during the study. Naturally, as the study shows, the lingonberries aren’t an obesity cure which work on their own as a way to remove fat, but they could be an ingredient which could enable you to gain less weight as part of a healthy diet.


 


The research took place using six-week old mice who were engineered to develop obesity and pre-diabetes. The mice were split into 10 groups of 12 mice, and for 13 weeks they underwent the following:


- 8 groups were fed a high fat diet, where 45 per cent of their calories came from fat. This diet was supplemented with eight different freeze-dried berries which were freely available to them.


- 1 control group was fed a calorie-matched high fat diet without the berries.


- 1 control group was fed a low-fat diet, with 10 per cent of their calories from fat without the berries.


 


The body weight and food intake of the mice was monitored weekly, and at the end of the study the blood samples were assessed for sugar, insulin levels, cholesterol and other fats. The researchers also looked at bodily organs, including the spleen and liver, to see how much fat had built up. The energy intake was very much the same across all of the groups, with the exception of those eating blackcurrant and bilberries, who ate more food and calories. But the fasting blood sugar levels were much lower in the lingonberry and blackcurrant groups than the high fat controls. Both of these groups had glucose and insulin resistance levels similar to the mice in the low-fat diet group. Researchers believe that the lingonberries either fully or partially prevent the detrimental metabolic effects of a high fat diet – blackcurrants and bilberries had similar properties but weren’t as effective. The conclusion of the study was that the beneficial metabolic effects of the lingonberries could be helpful in preventing obesity and disorders related to being overweight. As part of a balanced diet and a regular exercise programme, lingonberries could help to maintain a healthy weight and prevent obesity-related disorders from developing. As with any diet, it’s important that you speak to your GP before undertaking any extreme changes to your dietary habits, as it could be detrimental to your health. But there has been no proof that adding lingonberries to your diet can do you any harm, so in moderation they could be the weight loss answer you’ve been looking for.

A new study suggests that we can now burn fat with the combination of cold temperatures and chili peppers, providing effective weight loss. Researchers have found that exposure to low temperatures and the consumption of the chemicals found in chili peppers can increase the number and activity of brown fat cells, which burn energy. The study is the first to prove that the activity of brown fat cells can be induced in people who appear to have very few or no brown fat cells. The participants in the study who were also exposed to the cold also had less ‘bad’ white fat cells by the end of the study. Brown fat cells are currently the subject of intense research as the focus of anti-obesity drugs. In this new study, researchers exposed eight people with few brown fat cells to moderately low temperatures of 63 degrees Fahrenheit for two hours every day for the course of six weeks. Compared to the control subjects, who simply led a normal life, these people had around five per cent less body fat at the end of the study. They also burned more energy when they were exposed to the cold.


The researchers also looked at people who ate capsinoids, which are found in chilies, for six weeks. They found that these people also burned more energy than the control group when they were exposed to the cold temperatures, but they didn’t lose any more white fat than the control group. The experiment couldn’t have continued for long enough to see if there were any white-fat-burning effects on the compounds. The results of this study also help to explain the results of a previous study, which found that people who ate capsinoids had increased levels of fat breakdown. It was previously thought that brown fat, also referred to as brown adipose tissue (BAT), was only ever present in babies. But three independent research groups in 2009 found that brown fat cells do exist in the upper chest and neck of some adults. There is also another type of BAT known as beige fat, which is a subset of brown fat but formed from white fat cells.


Brown fat cells induced by the cold and capsinoids are likely beige fat, because they don’t show up on scans that are used to detect concentrated regions of brown fat cells. The study offers some interesting results because it suggests that chemicals which induce brown fat could be used to fight obesity. They would probably work better at keeping healthy people from becoming fat, rather than working as a diet alternative. However, with a rising obesity crisis, this could offer promising future developments. Capsinoids seem to induce brown fat in the same way as cold temperatures, by capturing the same cellular system that the body’s nervous system uses to create heat in the body. Developers are looking to create a drugs that activates this system, but capsinoids themselves won’t be used as they are a natural product and can’t be patented. The sweet chili peppers that capsinoids come from don’t actually taste hote, but they do produce the same physiological effects, such as making us sweat. Weight loss products are always popular with today’s society, and pharmaceutical companies are hopeful that this study could offer some inspiration for a new product to achieve the same effects in pill form.