Showing posts with label bone loss. Show all posts
Showing posts with label bone loss. Show all posts

Bones play many roles in your body — providing structure, protecting organs, anchoring muscles and storing calcium – but the problem is that they’re continuously changing. When you’re young it’s important to take care of bone health because your bones are growing and you need the optimum bone mass possible, and then after the age of 30 you start to lose bone mass, which increases your risk for fractures and osteoporosis — a condition that causes bones to become weak and brittle. As a general rule, the higher your peak bone mass, the more bone you have “in the bank” and the less likely you are to develop osteoporosis as you age, but a lot of factors can affect your bone health:


 


1. Calcium intake: You may have learned this years ago at school but that doesn’t mean you can put calcium away now you’ve graduated. Your calcium intake becomes even more important as you age as a diet low in calcium contributes to diminished bone density, early bone loss and an increased risk of fractures.


 


2. Physical activity: There’s no denying that exercise is good for your wellbeing; it helps you to maintain a healthy weight and prevent a myriad of health concerns – one of which being osteoporosis. If you don’t exercise regularly, your risk of this brittle bone disease is far higher than your more-active peers.


 


3. Smoking and drinking: According to recent research, tobacco weakens your bones, as well as doing all the other nasty things to your wellness that everyone knows about, so quitting is a solid idea. Moreover, if you drink more than two alcoholic drinks a day on a regular basis, you can increase your risk of osteoporosis. This is because alcohol can interfere with your body’s ability to absorb calcium.


 


4. Gender and age: Although it’s a common misconception that men don’t have to worry about osteoporosis, the fact remains that you’re at a greater risk of the brittle bone disease if you’re a woman. This is because women have less bone tissue than men, especially as you get older. The ageing process and menopause cause bones to become weaker and thinner, due to waning oestrogen levels. Again, this doesn’t mean that men are off the hook, but it does mean that older women have to be particularly vigilant about bone health.


 


5. Body type: If you’re extremely thin – meaning you have a body mass index of 19 or less – or have a small body frame, you’re also at an increased risk for osteoporosis. This is due to the fact that you have less bone mass to draw from as you age.


 


6. Race and family history: People of Asian descent and white people are at the greatest risk of osteoporosis. In addition, if you have a parent or sibling who has osteoporosis, you are also put at a greater risk — especially if you also have a family history of fractures.


 


7. Hormone levels: As we’ve previously mentioned, bone loss increases dramatically at menopause for women due to your dropping oestrogen levels but, for the same reason, your osteoporosis risk is increased if you suffer from amenorrhea. This occurs prior to menopause and is categorised by prolonged periods (of time) in which you do not menstruate. For men (see, I told you men weren’t off the hook) low testosterone levels can cause a loss of bone mass. Plus, no matter who you are, if you have too much thyroid hormone, you can also experience increased bone loss.


 


8. Health conditions: Stomach surgery (gastrectomy) and weight-loss surgery can affect your body’s ability to absorb calcium, as can conditions such as Crohn’s disease, celiac disease and Cushing’s disease. Moreover, if you have anorexia or bulimia, you are at further risk of bone loss.


 


9. Medications: If you take corticosteroid medications, such as prednisone, cortisone, prednisolone and dexamethasone, over a long period of time, you are causing damage to your bones. Other drugs that may increase the risk of osteoporosis include aromatase inhibitors to treat breast cancer, selective serotonin reuptake inhibitors, methotrexate, some anti-seizure medications and proton pump inhibitors.

As you get older, wellness experts are likely to blame your waning testosterone levels for your loss of muscle, energy and sex drive, but oestrogen might be getting off scot-free as a result. This is according to a new study, published in The New England Journal of Medicine, which found that your decrease in oestrogen may play a bigger role in your age-related health concerns than previously thought.


 


The study found that declining levels of oestrogen can have a negative effect on your wellbeing, leading you to accumulate more body fat – which is something that we previously blamed testosterone for. Study researcher Dr. Joel Finkelstein, an endocrinologist at Massachusetts General Hospital in Boston, commented, ‘The function of oestrogen in men has largely been ignored,’ as research has largely limited the study of the hormone in men to the role of oestrogen deficiency in bone loss. He added, ‘Men make oestrogen from testosterone, and women do, too,’ which is why your levels of both hormones naturally drop.


 


400 healthy men aged 20 to 50, all of whom had normal testosterone levels, took part in the study. These participants were injected with a drug that drastically lowered their normal production of the hormone, until the testosterone reached pre-puberty levels of production. 198 men were then given a 16-week supply of testosterone gel for their skin, in one of four dosage levels or a placebo. Similar doses of the gel were given to the other 202 volunteers, but these men also took a drug designed to block the conversion of testosterone into oestrogen over the 16-week study.


 


The divvying out of the gel and drug doses was arranged in such a way as to tell the researchers which symptoms – changes in body fat, muscle mass, strength and sexual function – were to do with reductions in testosterone, oestrogen or both. The researchers also arranged the study in this way to determine the level of testosterone at which these physiological effects occur. The results revealed that when oestrogen levels drop, men experience some of the same consequences that women do after menopause; increased bone loss, lowered libido, and more fat around the midsection.


 


While changes in strength and muscle mass and size were closely connected to lower testosterone levels, it was the decline of both testosterone and oestrogen that reduced the men’s sex drive and erectile function. Finkelstein noted, ‘We were surprised at the dramatic effects that low levels of oestrogen had on fat accumulation and sexual function in men. We knew that these effects were seen in studies on mice, and these results very accurately predicted what occurred in humans.’


 


According to Dr. Bradley Anawalt, an endocrinologist and professor of medicine at the University of Washington Medical School in Seattle, who was not involved in the research, ‘This is a beautifully done study that allows physicians to get a little better handle on interpreting testosterone levels, but the real mind-blower of this study is the idea that oestrogen has an important role in male physiology.’ Anawalt went on to say that the study has very important implications for medical practice, as the results clearly show how testosterone has a differential effect on body organs, such as fat, muscle, the penis and the brain.


 


With the results of this study, your doctor will be better able to understand the threshold levels of testosterone in the blood associated with age-related complaints, and at what levels testosterone therapy may benefit you. However, Anawalt warned that the study is limited by the fact that it used the average “normal” level of testosterone in men (300 to 900 nanograms per decilitre) to measure treatment outcomes in the participants, so your doctor needs to be careful about applying these results to you as an individual.